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Example Input Mode:
Partner Data
CBIS
Matrix
Example Data Type:
Secondary Screen (Kd)
Primary Screen(% control or competition)
If the input file contains Primary and Secondary Data, use:
Primary
Secondary
Assay Data File:
.txt or .csv format - download examples:
Bromodomain
Kd
Primary
To highlight spots, select a compound(s), click 'fill' and select entries.
Create Images for:
AB-1010
Highlight These Spots (
fill
):
AB-1010|ABL1-nonphosphorylated|2.1
AB-1010|ABL2|110
AB-1010|BLK|150
AB-1010|CSF1R|7.6
AB-1010|DDR1|8.7
AB-1010|DDR2|26
AB-1010|EPHA3|2500
AB-1010|EPHA8|1800
AB-1010|ERBB2|1200
AB-1010|FGR|640
AB-1010|FRK|87
AB-1010|FYN|140
AB-1010|HCK|690
AB-1010|KIT|8.1
AB-1010|LCK|31
AB-1010|LYN|61
AB-1010|PDGFRA|25
AB-1010|PDGFRB|8.4
AB-1010|PIM1|1300
AB-1010|PIM3|720
AB-1010|RIOK2|1700
AB-1010|SRC|900
AB-1010|YES|570
AB-1010|ZAK|770
AB-1010|ABL1-nonphosphorylated
AB-1010|ABL2
AB-1010|BLK
AB-1010|CSF1R
AB-1010|DDR1
AB-1010|DDR2
AB-1010|EPHA3
AB-1010|EPHA8
AB-1010|ERBB2
AB-1010|FGR
AB-1010|FRK
AB-1010|FYN
AB-1010|HCK
AB-1010|KIT
AB-1010|LCK
AB-1010|LYN
AB-1010|PDGFRA
AB-1010|PDGFRB
AB-1010|PIM1
AB-1010|PIM3
AB-1010|RIOK2
AB-1010|SRC
AB-1010|YES
AB-1010|ZAK
AB-1010|ABL1-nonphosphorylated|2.1
AB-1010|ABL2|110
AB-1010|BLK|150
AB-1010|CSF1R|7.6
AB-1010|DDR1|8.7
AB-1010|DDR2|26
AB-1010|EPHA3|2500
AB-1010|EPHA8|1800
AB-1010|ERBB2|1200
AB-1010|FGR|640
AB-1010|FRK|87
AB-1010|FYN|140
AB-1010|HCK|690
AB-1010|KIT|8.1
AB-1010|LCK|31
AB-1010|LYN|61
AB-1010|PDGFRA|25
AB-1010|PDGFRB|8.4
AB-1010|PIM1|1300
AB-1010|PIM3|720
AB-1010|RIOK2|1700
AB-1010|SRC|900
AB-1010|YES|570
AB-1010|ZAK|770
clear
Select Highlight spots color from Pallette:
(also used in table view)
Tree Image Options
Restore default options
Spot options:
IndianRed
PaleGreen
Gold
PowderBlue
Fill?
Outline?
Outline thickness:
1
2
3
4
5
Select Spots Color from Pallette:
(spot highlight color below)
micro
nano
Spot Size:
Scaling Factor:
.1
.2
.3
.4
.5
.6
.7
.8
.9
1
1.1
1.2
1.3
Area increase factor:
100%
90%
80%
70%
60%
50%
(per change of 10x Kd or 10% Competition)
Legend options:
Left align Text
Right align Text
Label options:
Compound Name?
Compound Name Font:
.5
1
1.5
2
Show Assay Panel information?
Show Panel Spots?
Append Concentration? (i.e., 'AB500@1000nm'; check before loading.)
Background Image:
Target labels?
Dark Tree Branch image?
Hide Lipid, Mutant, ATypical and Pathogen?
Spot options:
Spot Color transparency level:
none
low
medium-low
medium
high
no color
Spot Cutoff Value:
Kd (nM) (Blank for no cutoff)
Spot outline only?
Format:
JPEG(200KB per image)
Publication Quality(5MB image)
Create Publication Quality (5MB bitmap) Image for:
Select Compound
AB-1010
size/quality
100
90
80
70
60
50
40
30
% of original
White Space Border:
Yes
No
Preview and Highlighting
Highlight an assay by clicking on the spot or checking the box next to the Gene Symbol Name.
Click 'Update' to create the new images.
Compound To Highlight:
None
AB-1010
Highlight Panel?
* WildType kinase assays appear in both the main TREEspot and Mutant kinase dendrogams.
Human Kinome image created by KINOMEscan.
2 images created. To download (copy and paste) all images to your local machine click Open/Browse Image Folder.
Images Saved To:
D:\Eurofins\PROD\Applications\FrontOffice_Discovery\StudyManagement\TreeSpot\HTSTools\TreeImages\591_eouvv2nphi3iglhlkr5r31r3\
Open/Browse Image Folder
View Options:
(These options do not modify the images that have been created, only the view on this page)
AB-1010
Legend
Show Selected
Size:
Select Size
small
medium
full size
Images per Row:
1
Legend Resize?
Hover the cursor to identify spots and click to highlighted it. To save an image click the Zoom/Download link.
Zoom/Download
Highlight
Locate an Assay
ABL1-nonphosphorylated
ABL1-nonphosphorylated
ABL2
BLK
CSF1R
DDR1
DDR2
EPHA3
EPHA8
ERBB2
FGR
FRK
FYN
HCK
KIT
KIT
LCK
LYN
PDGFRA
PDGFRB
PIM1
PIM3
RIOK2
SRC
YES
ZAK
Legend
Data Table View:
Show All Data
Only Selected Compounds/Trees
TREE
spot
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